Sydney Morning Herald Q & A article published today:
The big questions
October 22, 2005/SMH
Why are experts so worried?
Viral outbreaks in animals are common, but the H5N1 bird flu virus causes serious disease in birds and has infected cats and other animals, and spreads rapidly. Although it has so far infected relatively few humans, the death rate has been high.
What is the chance that bird flu will become a human pandemic?
Most experts believe the risk of an imminent pandemic is about one in 10 - higher than at any recent time in the recent past. For a pandemic to occur, the H5N1 virus will have to adapt to spread efficiently among people.
In a pandemic, what is the individual risk of being infected?
That is impossible to say. The virus may spread readily through droplets in the air, or it may require more direct person-to-person contact. It may remain geographically isolated or spread quickly between communities.
Who would be most vulnerable?
Typically children and the elderly are disproportionately likely to catch flu and to have it severely, but there are exceptions: the 1918 Spanish flu was most lethal to young adults.
How is it spread?
So far, only people who have been working with or living close to birds have become ill, apart from one possible person-to-person transmission. The virus does not yet appear to spread via droplets in the air, but it may be transmitted through blood or faeces.
Is it possible to have a mild version of the disease?
Blood-testing in northern Vietnam has identified mild or symptom-free cases, sometimes clustered within families. This raises fears the strain may be adapting to humans and spreading between them.
What are the symptoms?
Among human cases of H5N1, fever and cough are the most universal symptoms and pneumonia can usually be seen at X-ray. Diarrhoea, vomiting and abdominal pain occur in about a quarter of cases. In fatal cases - half of all confirmed cases - lung failure is usually the cause. But the symptom profile is liable to change dramatically if the virus becomes an established human disease.
How is it treated?
Antiviral medicines such as Tamiflu probably help, though they may be needed in larger doses than currently recommended. An inhaled antiviral, Relenza, has not been tested yet in human H5N1.
Is it safe to eat chicken?
Poultry imports from affected countries are banned. Undercooked poultry meat from infected birds may spread infection to humans.
What's the good news?Vaccines, antivirals and intensive care should mean a good chance of survival in countries where these are available. Co-ordinated planning between government agencies, and mass communications to inform people about them, should minimise viral spread.
What would happen
Federal Government modelling predicts that if 25 per cent of the population was affected with flu - that is, a flu with a 25 per cent attack rate - and there was no immediate vaccine or treatment available, in six to eight weeks:
- 13,000 to 44,000 people would die.
- 57,900 to 148,000 would be in hospital.
- 2.6 million to 7.5 million would visit outpatient clinics.
http://www.smh.com.au/news/health/the-big-questions/2005/10/21/1129775959988.html