Thinking about it, I believe the first time I personally came across this particular nasty was about a month ago - on a college kid's computer. That one had all sortsa P2P stuff, of course, along with MIRC, ICQ and MessengerPlus, and plain old WinXP Home OEM, not even SP1 - no updates whatsoever - not even to the long-expired, never-activated 90-day trial of Norton AV that came on the thing. That machine was one of the worst I've ever seen; so screwed up format-and-reinstall turned out to be the practical answer - couldn't even make any headway using BARTPE; even the BIOS was corrupt. Since then, I've seen it several times, in various guises, all, as I recall, on machines lacking Windows and/or IE updates from around May-June of this year or earlier, as I mentioned, I've not seen a fully current SP2 machine affected - something which may just mean I haven't seen one yet.
The more I think about this, it seems to me it just might be related either to smitfraud or wintools, but that impression also could be due to the coincidence of finding all of them together on the same machines. While not an absolute, one fairly common coincident occurence is the presence of any or several of the
P2P/Filesharing apps known to be yuckware vectors, if not themselves actual carriers, and apart from being vectors for infection, many in fact bear yuckware incorporated into their code.
If I were better organized, I prolly could help you further track this one down, and I woulda noticed this one right off, but I ain't, and I didn't

- I generally take infected machines one-at-a-time, as presented. Most often, online scans, particular reputable free antiyuckware apps, and/or standard downloadable fixes clean things up pretty reliably, but once in a while, there comes along something a little trickier. This was one of them, and it took me a while to realize it.
In the troublingly tricky category, btw, are
Hidden Alternate Data Streams[/i][/u] and
rootkit-based exploits - fortunately, though very, very resistant to detection and cleaning, they're still relatively rare, and considerable ongoing effort among the antiyuckware community is bringing about more and more effective countermeasures. Its a war out there, and viruses no longer are the main enemy; they haven't gotten any tamer, but their freinds, relatives, and allies are getting meaner every day, with
Organized Crime taking an increasingly dominant role.