CRISPR: The end of Malaria and Zika and Mosquitoes

@edgarblythe,

think"how can we best enhance revenues?"

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@rosborne979,

and just as everyone states how we shall be ******* with evolution, we do not know how the edited genes will interact with gene expressions in the future.

Im sure the Chinese will be producing people like ants {: )

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@farmerman,

These are the first baby steps on the tip of the iceberg and they are already powerful and dangerous. I think Crispr types of gene manipulation are going to shake the foundation of population genetics and of life on this planet.

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Genetically Modified People Are Walking Among Us

https://www.nytimes.com/2018/12/01/sunday-review/crispr-china-babies-gene-editing.html?rref=collection%2Fsectioncollection%2Fhealth&action=click&contentCollection=health&region=stream&module=stream_unit&version=latest&contentPlacement=9&pgtype=sectionfront

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A recent Article:

https://www.cnet.com/news/the-crispr-machines-that-can-wipe-out-entire-species

from the article wrote:

But that occurred in a time before a monumental, global upheaval in genetic engineering: the invention of CRISPR/Cas9 (or more simply "CRISPR") in 2012. CRISPR is a powerful genetic engineering tool, often referred to as a "pair of molecular scissors," because of how precisely it can cut and edit genes in almost any species.

And two years later, it would be CRISPR — and a turtle — that provided a Boston geneticist with a world-changing idea.... [portions removed]...

So in taming evolution, humanity is now the arbiter of the genetic realm. We've not just entered the game of genomes, we've ascended the throne. And though their release is likely several years away yet, our ability to craft CRISPR machines that drive species extinct or change them forever was something we could not have dreamed about just five years ago.

It isn't winter that's coming, but a revolutionary spring.

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@rosborne979,

Id be gld to see the Emerald Ash Borer, the Marmorated Stinkbug, and the Spotted L:anternfly have a gene driver take a shot at distributing edited Apoptosis genes into their genomes and DIE.
The Intelligent Designer has given us so many invasive species in the Post Columbian Species Exchange.

Also, maybe we can give flippers to polar bears, noooo, juss kidding on that one.

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And I was being reckless by thinking maybe we could get by with murdering the mosquitoe.

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@Leadfoot,

Leadfoot wrote:

And I was being reckless by thinking maybe we could get by with murdering the mosquitoe.

Yes, FM seems to have a bit of insecticidal behavior hidden away.

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I see the scientific establishment has come out firmly against the way the Chinese researcher used CRISPR to alter human children. In this case I think they are right. It was dangerous and served no real purpose.

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@Leadfoot,

Do you think that having anyone come out against it will stop it from happening?

Do you think that this one case that we know about is the only one that has happened (and is happening)?

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@rosborne979,

The cure for cancer will come out of a better understanding of how to manipulate the human immune system - that will probably not require any genetic modification.

But also if genetic science becomes so advanced that the average person can afford to do a bit of genetic house keeping every so often, that will go a long way to prevent cancer ever forming in the first place!

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@mystikmind,

think about it. sickle cell and immunity to malaria are genetic manipulation of the immune system. genetics controls the other.

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@farmerman,

I though sickle cell anemia was an evolutionary defense to malaria?

That comes under the general heading of breeding genetics. It is not direct manipulation of genetics and your limited by the current gene pool. So, for example, you can breed a tastier cow, but you can never breed a cow that can lay eggs, since the genes for doing that simply do not exist in the bovine gene pool.
Genetic manipulation on the other hand..... milk eggs anyone?? Anyone?

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@rosborne979,

Quote:

Do you think that having anyone come out against it will stop it from happening?

No, not at all. You can never remove a determined person's free will so someone with the ability (or without), will no doubt do it. With the ability for any John Doe to order lab made DNA sequences and sophisticated lab equipment available to anyone with money, I could in fact start doing it myself.

My guess is that Chinese CRISPR hackers will get the same treatment as other trouble makers in the aftermath of this story. China does not like to look scientifically unsophisticated and that incident made them look that way. They can do far more to police this activity than we can. Check out how successful they've been in keeping those pesky religions under control. No mixing of church & state to fear there. They handled the Buddhists awhile back and are now making progress on the Christian problem. Harder to exile the leader in that case though.

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@mystikmind,

youve just tried to take up polar ends of the same argument, and since Im on vacation from common sense Im having pizza.

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@farmerman,

Why didn't you tell me sooner that you are the all knowing all seeing center of all wisdom and knowledge of the universe.... Please tell me more about what i am doing, look i am now on bended knee, I like to be told all the mysterious things i had no idea i was doing? And while you are at it can you tell me i am writing the correct numbers on my lotto entry ticket i am doing rite now, i would love to know that too??

Edit: oh wait, your on vacation, i guess my lotto win will have to wait, sigh.

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@mystikmind,

just make a perfect act of contrition and send a few hundred dollars to the following website FARMERMAN'S FUND FOR THE INCOORIGEABLE

As far as lottery tickets, why would I make your day after you get done insulting me? (If you can answer that question in a non-smartass fashion maybe Ill reconsider but you are then contractually bound to share your winnings with me 50/50) K?

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@farmerman,

Oh dear me, yes i apologize for responding to your smartass insulting comment with some light sarcasm.

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@mystikmind,

Quote:

think about it. sickle cell and immunity to malaria are genetic manipulation of the immune system. genetics controls the other.

That was my first response to you. You consider it insulting eh??

You dont like to be told when youre incorrect?

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@farmerman,

Oh wow, this is a 'DITTO' moment if ever i saw one!

I toned my response to be equally as insulting as yours, that is my answer.... not that either of them was what i would call 'insulting' but since YOU chose to lower the bar on that well, then yes it is.

Edit: oh and buy the way, just saying someone is wrong just because 'you say so' does not make them wrong. It requires logical reasoning, which i do not see?

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CRISPR: The end of Malaria and Zika and Mosquitoes

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