virus related problems

I have had a virus in the past that I was able to get rid of by using Norton Antivirus. Approximately a year later it suddenly detected another virus. I feel was related to the first. Now the viruses are likely gone but the effects are still able to be seen in norton. I am prevented from using norton disk doctor and get the message "The operating system, or another process, currently has exclusive access to this drive, or some of its files." Some other problems that I find:
I have been using adaware, norton and others regularly. I am still having problems with internet explorer hanging up. Most recently when I try to delete my internet history using control panel/internet options/clear history the history files are still viewable in norton system works/web tools/advanced cleanup (2004 version). I mentioned the internet explorer hangup, I know that it hangs up because when I click on the begin quick clean button after running IE I get a message stating that I still have a window open (none visible even in ctl/alt/del applications window). I am not sure if I still have a bug in the system or permanent changes were made when I did have the virus (eliminated following directions from norton)(Backdoor.Rsbot).
The virus essentially opened my web service and generated internet explorer pages until my machine froze and opened my email associated with my web service and send a bunch of emails. fortunately I don't use that email service. I will post below hijack this log file if that will help. Thanks for reading all of this and your help in advance.
eng02004
Logfile of HijackThis v1.97.7
Scan saved at 8:58:09 PM, on 5/28/2004
Platform: Windows XP SP1 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP1 (6.00.2800.1106)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\LEXBCES.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\Symantec Shared\ccSetMgr.exe
C:\WINDOWS\system32\LEXPPS.EXE
C:\Program Files\Common Files\Symantec Shared\ccEvtMgr.exe
C:\WINDOWS\System32\LXSUPMON.EXE
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\Program Files\Common Files\Symantec Shared\ccApp.exe
C:\Program Files\Norton SystemWorks\Password Manager\AcctMgr.exe
C:\WINDOWS\System32\ctfmon.exe
C:\Program Files\BigFix\BigFix.exe
C:\Program Files\wmconnect\wmtray.exe
C:\Program Files\Microsoft Office\Office10\msoffice.exe
C:\WINDOWS\System32\PackethSvc.exe
C:\Program Files\Common Files\Symantec Shared\ccProxy.exe
C:\MATLAB6p5\webserver\bin\win32\matlabserver.exe
C:\Program Files\Common Files\Microsoft Shared\VS7Debug\mdm.exe
C:\Program Files\Norton SystemWorks\Norton Antivirus\navapsvc.exe
C:\PROGRA~1\NORTON~2\NORTON~3\NPROTECT.EXE
C:\Program Files\Norton SystemWorks\Norton Antivirus\SAVScan.exe
C:\PROGRA~1\NORTON~2\NORTON~3\SPEEDD~1\NOPDB.EXE
C:\Program Files\Common Files\Symantec Shared\CCPD-LC\symlcsvc.exe
C:\Program Files\Messenger\msmsgs.exe
C:\Program Files\wmconnect\wwm.exe
C:\Program Files\Internet Explorer\IEXPLORE.EXE
C:\Documents and Settings\eric\Local Settings\Temp\Temporary Directory 5 for cwshredder.zip\CWShredder.exe
C:\Documents and Settings\eric\Local Settings\Temp\Temporary Directory 2 for hijackthis.zip\HijackThis.exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.emachines.com
O2 - BHO: (no name) - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 6.0\Reader\ActiveX\AcroIEHelper.dll
O2 - BHO: Web assistant - {9ECB9560-04F9-4bbc-943D-298DDF1699E1} - C:\Program Files\Common Files\Symantec Shared\AdBlocking\NISShExt.dll
O2 - BHO: NAV Helper - {BDF3E430-B101-42AD-A544-FADC6B084872} - C:\Program Files\Norton SystemWorks\Norton Antivirus\NavShExt.dll
O3 - Toolbar: &Radio - {8E718888-423F-11D2-876E-00A0C9082467} - C:\WINDOWS\System32\msdxm.ocx
O3 - Toolbar: Norton AntiVirus - {42CDD1BF-3FFB-4238-8AD1-7859DF00B1D6} - C:\Program Files\Norton SystemWorks\Norton Antivirus\NavShExt.dll
O3 - Toolbar: Web assistant - {0B53EAC3-8D69-4b9e-9B19-A37C9A5676A7} - C:\Program Files\Common Files\Symantec Shared\AdBlocking\NISShExt.dll
O4 - HKLM\..\Run: [LXSUPMON] C:\WINDOWS\System32\LXSUPMON.EXE RUN
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
O4 - HKLM\..\Run: [ccApp] "C:\Program Files\Common Files\Symantec Shared\ccApp.exe"
O4 - HKLM\..\Run: [AcctMgr] C:\Program Files\Norton SystemWorks\Password Manager\AcctMgr.exe /startup
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\System32\ctfmon.exe
O4 - Global Startup: BigFix.lnk = C:\Program Files\BigFix\BigFix.exe
O4 - Global Startup: Microsoft Office.lnk = C:\Program Files\Microsoft Office\Office10\OSA.EXE
O4 - Global Startup: Wal-Mart Connect Tray Icon.lnk = C:\Program Files\wmconnect\wmtray.exe
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\Office10\EXCEL.EXE/3000
O9 - Extra button: AIM (HKLM)
O9 - Extra button: Real.com (HKLM)
O9 - Extra button: Messenger (HKLM)
O9 - Extra 'Tools' menuitem: Messenger (HKLM)
O14 - IERESET.INF: START_PAGE_URL=http://www.emachines.com
O16 - DPF: DigiChat Applet - http://host5.digichat.com/DigiChat/DigiClasses/Client_IE.cab
O16 - DPF: {3E68E405-C6DE-49FF-83AE-41EE9F4C36CE} (Office Update Installation Engine) - http://office.microsoft.com/officeupdate/content/opuc.cab
O16 - DPF: {74D05D43-3236-11D4-BDCD-00C04F9A3B61} - http://a840.g.akamai.net/7/840/537/2003120501/housecall.antivirus.com/housecall/xscan53.cab
O16 - DPF: {9522B3FB-7A2B-4646-8AF6-36E7F593073C} - http://a19.g.akamai.net/7/19/7125/1435/ftp.coupons.com/v3123/cpbrkpie.cab
O16 - DPF: {9F1C11AA-197B-4942-BA54-47A8489BB47F} (Update Class) - http://v4.windowsupdate.microsoft.com/CAB/x86/unicode/iuctl.CAB?38028.8036458333
O16 - DPF: {C2FCEF52-ACE9-11D3-BEBD-00105AA9B6AE} (Symantec RuFSI Registry Information Class) - http://security.symantec.com/SSC/SharedContent/common/bin/cabsa.cab
O16 - DPF: {CE28D5D2-60CF-4C7D-9FE8-0F47A3308078} (ActiveDataInfo Class) - https://www-secure.symantec.com/techsupp/activedata/SymAData.dll
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab
O17 - HKLM\System\CCS\Services\Tcpip\..\{53114895-DB9B-4EE5-BD38-4CADA3A48F65}: NameServer = 205.188.146.146