That would be tricky because I'm not able to see what I'm clicking on from the front of the room. I've got the computer and projector in dual screen mode, so the projector is always showing the slides while iTunes is on the computer. To see what I'm clicking on, I would have to walk over to the computer anyway.
I suppose I could have the computer and projector mirror each other so that everything is one screen. But in that scenario, when I want to stop or start an audio track I would have to bring the iTunes window to the front of the screen for a moment, which means everyone would lose sight of the Powerpoint slide during that time. Not a tremendous problem but something tells me that would distract the students even more than my walking back and forth between different parts of the room.
The ideal situation would be to have my computer at the front of the room with me, I guess, but I think the IT folks would rather try to find a remote than get all of the necessary extension cords (one for the computer's power, one for the audio, one for the projector, etc.).