@Questioner,
I have defined the term ‘ignorance’ in this particular way: that it is literally ignoring the true nature of reality. It not to be understood to be a lack of knowledge about the true nature of reality. Each one of us misunderstands reality’s true nature in our own individual way and all our sufferings arise from our personal misunderstanding of reality. This leads to actions of body, speech and mind that are based on an erroneous view, and eventually result in suffering. Since Buddhists do not believe in non-existence (because it cannot be found) the results of actions may not arise in this lifetime but in a future life.
Wisdom develops by removing our misunderstanding about reality’s true nature. For example if we have an extreme view such a Nihilism or perhaps eternalism this will cloud our ability to develop the wisdom that realizes the true nature of reality. We deliberately choose to develop these views thus ignoring the true nature of reality which is not either of these extreme views.
To realize what the true nature of reality is, we need to get an overview of the fundamentals of Buddha’s teachings. This is not surprising for example a surgeon would not attempt to operate on someone without first learning about anatomy and surgical techniques. But the, would be, surgeon starts with the wish to become a surgeon, learns the path to becoming one, and if able, follows the necessary path to that goal. If we want to put an end to the root cause of suffering then we need to first understand the path intellectually and then follow the path but only when we first have a intellectual, fundamental, overview. A good place to start is the Four Noble Truths.
The First is that: 'All is suffering'. If you want I could try to explain the first of the Four Noble Truths?