@Mr Fight the Power,
Mr. Fight the Power wrote:The advancement of science has lead to some observations that on first appearance seem unreasonable.
This has caused me to think about a series of epistemological questions:
First, is it possible for observation to be at odds with our reason?
I think this is a great question. Clearly it is possible for reason and empiricism to at least appear to be in conflict. It happens in physics all the time. As Feynman famously said, in physics the way we have to describe Nature is incomprehensible to us. Kant had this problem, for he reasoned that spacetime phenomena are unreal but observed that they are real. Personally, I think the problem is that he forgot that observation requires reasoning. He did not observe the reality of phenomena, he reasoned from his observations that they are real. Thus the conflict between reason and empiricism was only apparent. To answer your general question, I'd say that such conflicts are only ever apparent. In mysticism such conflicts do not arise, but in physics and philosophy they are everywhere.
Quote: Is any apparent conflict an error in our methods of employing one or both of these?
If I understand what you mean I'd say no, as long as we bear in mind that all inputs from our senses are value-laden. I doubt there is no such thing as a pure observation.
Quote:Second, if there is a valid conflict between the two, which do we accept?
In the case of a conflict I'd say it must always be our reason that is in error. Either we are misinterpreting our observations or making philosophical mistakes. Dialethists believe that there are true contradictions, but I'm not one of them.
Quote:Third, is it even possible to resolve conflict between the two, is it possible to even separate rational understanding from observation?
I'd say yes and yes. Understanding is not observation, and I don't believe there can ever be a true conflict between reason and empiricism.