@ossobuco,
When we were in Italy last year, we did hotels / B&Bs for a week, then 3 separate weeks in apartments.
Ist apartment was in Limonta, overlooking Lake Como. We found it on the 'net, through an agency (it was listed in a couple of places) The apartment itself was just fine - it ticked all our boxes. When we got there, there was an overwhelming smell of cigarette smoke - as if someone had locked themselves in and smoked themselves to death! This was despite it being advertised as non-smoking. Most of the time we were there we lived with the windows wide open - and I think we washed the curtains - to try and cut the smell. As a result of this, the apartment was cleaner when we left than when we arrived.
2nd apartment was in Tuscany, in a village outside Col de Val d'Elsa. This was also fine - and was rented through an agency in Australia. Mark spoke to the agent who was most helpful. No laundry in this one - but pay laundry in the complex.
3rd apartment was my favourite - a small apartment in the Canareggio district in Venice. I found the apartment on Slow Travel website, advertised, and someone had reviewed it. We rented direct from the English owners. The apartment was spotless, and the information supplied, including an unbelievable array of books, maps, etc., was fantastic. There was also a directory of the best places to shop, eat, and otherwise enjoy yourself in Venice.
All the apartments we took were very well kitted out - and lived up to their advertisements.
Except for Venice, the apartments cost roughly as much as a good standard double room in a hotel. However, the extra space, cooking facilities and other amenities certainly made them worthwhile.
I'd certainly do the apartment thing again. (France is next on my agenda!) In hindsight, we would look for apartments more in villages or towns. Our first two apartments were sort of in the country, so we couldn't wander off for a meal - it was always a drive. And you needed a car to get there.
Venice was perfect, local eateries aplenty, local providores, choice of vaporetto stops, easy walking everywhere. I'd go back there in a flash!
We rented 3 different ways - and couldn't really fault any of them (except the overwhelming cigarette smoke in the first one). I don't know if we were just lucky in our experiences or if this is normal.