@Frank Apisa,
Frank,
The only answer I can give you is from a position where
your concept of "guess" is inextricably related to
your concept of "reality". The fact that certain aspects of concepts imply a "physical relationship" with other concepts does not imply for me anything significant about the "reality" of either concept. Physicality is merely a description of our expectancies of the nature of a relationship. It is not a "property" of an independently existing "thing".
The concepts of "an electron" and "an observer" serve to illustrate this because an electron is associated with different aspects of physicality according to what
you would call the "guesses" of different observers. Those who "guessed particle" got that relationship, but so did those who "guessed wave". In "naive" terms such "properties" were considered to be logically incompatible, but in non-dualistic terms observers and electrons are co-existent within a "particular observation event". So what might be "the
reality of electrons" for the layman(equates to the "
utility of the concept electron for predicting measurements for particular observers" for a scientist.
This summary of the celebrated "wave-particle dispute" should show you why labelling non-dualistic arguments as "blind guesses" is meaningless.
This is of course old turgid stuff. "Guessing" is what all observers do most of the time in daily life and what "works" for particular observers is called "the truth" for as long it is required. I am not going to repeat why "scientists" tend to agree as observers more often than others, but I will repeat that what scientists do NOT do is seek "truth"... they go for "best guess that works". The fact that some scientists might deny this merely indicates a degree of philosophical naivity on their part.