How the Human Got His Thumbs

Researchers from U.S. Department of Energy's Lawrence Berkeley National Laboratory, publishing online in the most recent issue of the journal Science, placed human, chimpanzee and macaque versions of the enhancer into mouse DNA. The scientists also added a gene that would release a blue dye to show where in the mouse fetus the enhancer was most active. When the mice developed, the researcher saw that it was active in the hands, feet and throat. Additionally, the mice with the human version showed the most activity, with the chimp version producing some activity, and the macaque version producing very little.