H. P. Lovecraft had a horror story about aliens that extract human brains and keep them alive in jars:
The Metallica song Trapped Under Ice
was supposed to be about a guy who had his head cryogenically frozen in the hopes of being resurrected one day, but found that he was still conscious and trapped inside his frozen head without being able to communicate his plight to anyone:
Here's an interesting dilemma. What if before you die science develops an ability to keep your brain alive indefinitely, but they don't yet know how to attach it to any sensory input. But if you were willing to endure some 500 years of endless dark silence they will eventually develop the ability to connect you to machines that will allow you to perceive and interact with the world.
Would it be worth 500 years of endless dark silence to be able to live again (possibly for a very long time) once they got things working?
Or would the torture of being totally alone and cut off for 500 years be too much to bear no matter what the rewards?