hereditability and variability of chromosomes in sex cells

Holy Grail!

Academia says not (To your actual question)

But, it appears otherwise, so it seems.

Can Dna alter?

Does it regurgitate itself physically, energetically, or both?
Or does it alter via external/internal experience?

Being in the bubble, prevents the recognition of that which is not of the bubble.

If you remove/add a distinct peptide, protein, nutrient to a system - Does it ignore it, defend itself against it, assimilate it, or curl up and die?

As a lifeform it will self-preserve.
You decide.