Wasn't there some sort of evidence for the role of damaged microtubules in the onset of this disease?
I believe so. Most of my information comes from reading and conversations with friends doing research at the Gladstone Institute in San Francisco. Their focus is on the cultivation of stem cells and their applications to possible therapies for heart disease, Alzheimer's & Parkinson's diseases. I'm sure that focus influenced some of the content. Interestingly they have made rapid progress with respect to the regrowth of heart muscle tissue (replacing the scar tissue growth after a coronary attack) using these therapies, and they believe they may be a couple of years away from analogous neuron replacement therapies (or alternatively replacing the protein variant associatred with increased incidence of Alzheimers).