What? No takers?
How disappointing!
OK, I'll go first, then.
It would have to be Janette Turner Hospital's
Due Preparations for the Plague. Let me tell you, it was brilliant, engrossing, moving, scary, uplifting ... everything!

I honestly could not stop reading, once I'd started.
Due Preparations has been described a "thriller" but it is so much more than that. It embraces contemporary politics, terrorism, espionage, love ... the lives of real people coping with loss & other devastating predicaments, seeking atonement, redemption for things they have done .... yet somehow it manages (after taking us well & truly through the wringer!
Phew!) the conclusion leads us to continue remain hopeful, to hang onto optimism despite the terrible things that have occurred.
Best book I've read in ages!
Reviews:
http://www.janetteturnerhospital.com/reviews/plague.htm