I long lived in southern Illinois. I had heard various estimates of the stress in that fault. While living there, in 1987 or -88 (i don't recall specifically) there was a "tremblor" (i think that is the correct term) which was not horribly damaging, but which was enough to throw me out of bed. The news reports thereafter reported that there was in excess of thirty feet of stress in the New Madrid fault. That is to say, the relative shift between the plates would have been thirty feet of rotation, were there no impediment to the movement.
There has been no major seismic activity in that fault since the quakes of 1811-12. It is considered to be long overdue.
There is another aspect of that situation which gets overlooked, but which came to my attention in reading something quite apart from the subject of seismology. I was reading Freeman's
R. E. Lee. When the quakes of 1811-12 had subsided, the Mississippi River began to move east below the confluence of the Missouri and Illinois Rivers. In the late 1830's, when the Corps of Engineers were working on a vast project to improve the navigation of the Mississippi, an estimate was made that the continued migration of the Mississippi would leave St. Louis fifteen miles inland from the river by 1960. By 1840, there was already more than one hundred feet of muddy river bed exposed between the St. Louis docks and the river's edge at times of low water. The citizens of St. Louis petitioned the Congress to fund a project of the Corps of Engineers to "correct" the course of the river. They were turned down, but the Corps agreed to provide an officer if they would fund the project. Ten thousand dollars were raised by private subscription, and a not so young Lieutenant of Engineers, Robert Lee, was assigned to the project.
His solution was simple and direct. Using a low-tech steam pile driver mounted on a river boat, and the massive trunks of the "big butts"--the giant trees of the bottom land of southern Illinois--he constructed two wing coffer dams, one of about a mile in length and the other about a mile and a quarter in length. A wing coffer dam is a line of pilings which juts out into the river at an angle to the river bank. The natural action of the river fills the coffer dams with débris and silt, and soon the "Father of Waters" was again flowing in its old bed, and had returned to the Missouri side at St. Louis.
There was no one living in that portion of Illinois at the time, and a land owner on the Illinois side who brought suit lost his case. Since then, however the cities of East St. Louis and Belleville have been built on the ground formed by Lee's wing coffer dams. I have often thought about the scale of the disaster if a major earthquake strikes the region, and those buried wing coffer dams give way.
Here is a link to Wikipedia's article on the New Madrid fault.