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Oocyte development, meiosis and aneuploidy

 
 
Reply Tue 5 Sep, 2017 08:50 am
I´m writing this blog because after reading an article about Meiosis a few questions have been raised that I feel I could get the answer here since there are many people who work on the evolution of genetics.
My question is the following:

Taking into account that the chromosomal cross linking frequency is less regulated in female humans as compared to men and is generally responsible for the aneuploidy in oocytes , female chromosomes often intertwine in sites that men chromosomes normally would not. This sometime leads to multiple genetic disorders and even premature abortions. Are women, who have less regulated meiotic division, the main culprits responsible for genetic variation in the human race?
-MacLennan, M., Crichton, J. H., Playfoot, C. J., & Adams, I. R. 2015. Oocyte development, meiosis and aneuploidy. Seminars in Cell & Developmental Biology, 45, 68- 76. doi: http://dx.doi.org/10.1016/j.semcdb.2015.10.005
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Type: Question • Score: 2 • Views: 270 • Replies: 2

 
jespah
 
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Reply Tue 5 Sep, 2017 08:58 am
@pipevalencia ,
Actually, there's probably nobody on this website who works on the evolution of genetics.
tsarstepan
 
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Reply Tue 5 Sep, 2017 12:13 pm
@jespah,
And a single thread/post on a random forum doesn't actually make a blog either.
pipevalencia wrote:

I´m writing this blog....
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