@Mu ,
Well, you really have no idea what they talk about behind closed doors. You also have no idea what Anna, etc. were saying, etc. Who knows? Why assume they were poking fun at you without evidence?
BTW, I know fully well what it's like to have Queen Bee type of teenaged girls make fun of me and my friends. I lived it. And it is rather unpleasant. However, it is also fleeting and keep in mind their lives are shallow and stupid if they are so petty as all that. If they are at all. Maybe they were whispering about your teacher or the local sports team for all you know. Right now, all you have is your own speculation. So operate under the assumption they were yakking about what was on TV the night before unless you have hard evidence otherwise, okay? Otherwise, it's maddening.
Don't give them that kind of power over your thoughts and moods.
Maybe the thing to do is to start communicating with your brother again. It does not need to be about anything heavy. It does not have to be about Anna. There are a trillion other topics. Make it one of them. So talk about school or the movies or the weather or gaming or music or your parents or whatever. Keep it light.
Why am I suggesting that
you be the one to offer reconciliation, rather than wait for him? Because you aren't the one who's depressed and going untreated. And because when, inevitably, he and Anna break up, he's going to need you.
Your brother needs to know he can count on you.