@alius,
I believe it is US (American) "gangsta" or "ebonic" (black slang) dialect.
We don't give a **** = We (emphatically) do not care
where = same as normal English
dem = those
hoes = whores = women (widely considered to be insulting - "whore" means "prostitute" in regular English. "Ho" is a term used in the deeply misogynistic (woman-hating) "gangsta" culture)
"Where someone/people [is/are] at" can mean where they are located, or what they are thinking or doing or planning or about to do...
Thus:
We don't care where those women (or girls) are.
Or
We don't care what those women (or girls) are doing.
We don't care what those women (or girls) think.
We don't care what those womens' (or girls') opinion is.
More context needed, really...
Sounds like it's from a rap song maybe?