kratom shot If you're taking painkillers now for pain relief whether they are over-the-counter painkillers or opioid narcotic painkillers, there are a few things you should know about the damage that can occur to your kidneys. My assistant in her twenties is on kidney dialysis now and waiting for a kidney transplant due to taking over-the-counter analgesic painkillers. Many people think this must be a rare occurrence but there are hundreds of people who are on kidney dialysis or received transplants or have died due to kidney damage or kidney failure from painkillers.