Lovatts Colossus 134 Giant Cryptic

Hi fellow puzzlers, need some help please
25d Does he have a cast iron empolyment agreement? (11) = METTLEO??ER
(I thought Mettle tight) I,m pretty happy with METTLE but rest of word is crossed with from the O 43a = With extreme control, out to gain influence = clOut 48a When day broke, transplanted organ (8) Keyboard
51a Break from ritual and hide psychic ability (7) = respitE 54a Reach for bone (6) = Radius

screwed up somewhere
cheers
smithy