mistrust(ful) vs distrust(ful)

Distrust and mistrust are roughly the same. Both could mean (noun) lack of trust, and (verb) to regard without trust. But distrust is often based on experience or reliable information, while mistrust is often a general sense of unease toward someone or something. For example, you might distrust the advice of someone who has given you bad tips in the past, and you might mistrust advice from a stranger. This distinction is only a general tendency, though, and it is not always borne out in real-world usage.

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