@Procrustes,
Perhaps. There's an irony in this, because every day we meet individuals who are so sure they are right in what they know, and walk around in self-justified misery. They just don't understand. All we can know is illusion because at the base of it all is the knower, to whom knowledge is merely a function. Without that context, all we know is useless. So if what you think you know makes you miserable, what is the greater sacrifice; admitting to yourself that you might be wrong, or enduring a life that you understand to be miserable? To me the answer is simple...